Ramsey Research GroupThe University of North Carolina at Chapel Hill

Department of Chemistry

Recent Group Member Presentations

(post 2009)

65th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN (June 2017)

Dmitriy Chernookiy and J. Michael Ramsey
“Multipole Field Effects on Cylindrical Ion Trap Performance at High Background Pressures” (Oral)

Yury Desyaterik, John Perry, Tina E. Stacy, Jean Pierre Alarie, Kevin Schultze and J. Michael Ramsey
“Coupling of Microfabricated GC Columns with a High Pressure Ion Trap Mass Spectrometer” (Poster)

Kristina M. Herrera and J. Michael Ramsey
“Low Temperature Hydrogen Exchange Microchip Capillary Electrophoresis-Mass Spectrometry” (Poster)

Justin Godinho and J. Michael Ramsey
“Characterization of Anions by Microchip Capillary Electrophoresis-Negative Electrospray Ionization-Mass Spectrometry” (Poster)

Gregory F. Brabeck and J. Michael Ramsey
“Determination of Ion Secular Frequency Bandwidth in Micro Ion Trap High Pressure Mass Spectrometers” (Poster)

41st International Symposium on Capillary Chromatography, Fort Worth, TX (May 2017)
Justin Godinho and J. Michael Ramsey
“Microchip Capillary Electrophoresis-Negative Electrospray Ionization-Mass Spectrometry for the Characterization of Anions” (oral)

Pittcon 2017, Chicago, IL (March 2017)

Davey L. West, William H. Henley, and J. Michael Ramsey
“Microwell Device Development for the Transfer, Isolation, and PCR Validation of Whole Cells” (poster)

64th American Society for Mass Spectrometry Conference on Mass Spectrometry
San Antonio, TX (June 2016)

William M. Gilliland and J. Michael Ramsey
“Development and Applications of Microchip Capillary Electrophoresis Coupled with High Pressure Mass Spectrometry” (oral)

Andrew Hampton and J. Michael Ramsey
“Improving the Selectivity of a High Pressure Mass Spectrometer” (poster)

Zachary A. Dyer, Kenion H. Blakeman, Craig A. Cavanaugh, Tina E. Stacy and J. Michael Ramsey
“Utilizing Silicon on Insulator Materials to Fabricate Miniature Ion Traps for High Pressure Mass Spectrometry” (poster)

Esme Candish, Michael E. Pacold, J. Scott Mellors and J. Michael Ramsey
“Intact Phosphorylated Protein Analysis by Microfluidic CE-ESI-MS” (poster)

40th International Symposium on Capillary Chromatography, Riva del Garda, Italy (May 2016)

William M. Gilliland, J. Scott Mellors, and J. Michael Ramsey
Development and Applications of a Microchip CE-nESI-HPMS Platform (oral)

Pittcon 2016, Atlanta, GA (March 2016)

Russell E. Bornschein, William M. Gilliland and J. Michael Ramsey
Electrospray Ionization-High Pressure Mass Spectrometry for Peptide and Protein Analysis (oral)

Andrew Hampton and J. Michael Ramsey
“High Frequency, High Pressure Tandem Mass Spectrometry” (poster)

12th Symposium on the Practical Application of Mass Spectrometry in the Biotechnology Industry (CASSS Mass Spec 2015), Brooklyn, NY (September 2015)

Erin A. Redman, J. Scott Mellors, and J. Michael Ramsey
“Intact Monoclonal Antibody Analysis via Microchip CE-MS” (poster)

William M. Gilliland, Jr., J. Scott Mellors, and J. Michael Ramsey
“Microchip Capillary Electrophoresis Coupled with High Pressure Mass Spectrometry for the Analysis of Amino Acids and Other Metabolites” (poster)

10th Harsh-Environment Mass Spectrometry Workshop, Baltimore, MD (September 2015)

Andrew Hampton and J. Michael Ramsey
“Improving the Selectivity of a High Pressure Mass Spectrometer” (oral)

63rd American Society for Mass Spectrometry Conference, St. Louis, MO (June 2015)

Bruno Coupier, Kevin Schultze, Sorin Mitran, and J. Michael Ramsey
“Rarefied Choked Flow in a Microscale Ion Trap Operated at High Pressure” (oral)

J. Scott Mellors, Michael Pacold, Elizaveta Freinkman, Erin A. Redman, and J. Michael Ramsey
“Microchip Capillary Electrophoresis with Integrated Electrospray Ionization for Rapid and Efficient Analysis of Polar Metabolites in Biological Samples” (oral)

Kenion Blakeman, Tina Stacy, Craig Cavanaugh, and J. Michael Ramsey
“Evaluating Ion Trap Materials for Hand Portable, High Pressure Mass Spectrometry” (poster)

Dmitriy Chernookiy, Bruno Coupier, and J. Michael Ramsey
“Optimization of the Cylindrical Ion Trap Geometry Operated at High Pressure” (poster)

Andrew Hampton and J. Michael Ramsey
“Manipulation of Trapped Ions in High Pressures in CITs and SLITs” (poster)

Erin A. Redman, J. Scott Mellors, and J. Michael Ramsey
“Separation and Characterization of Intact mAb Conjugate Charge Variants via Microfluidic CE-ESI with Online MS Analysis” (poster)

Pittcon 2015, New Orleans, LA (March 2015)

Kenion H. Blakeman, Tina E. Stacy, Craig A. Cavanaugh, and J. Michael Ramsey
“Improved Mass Resolution in Microscale Ion Traps for Hand Portable, High Pressure Mass Spectrometry (oral)

William Black, J. Scott Mellors, and J. Michael Ramsey
“Integrating SPE with Microchip CE-ESI” (oral)

Craig A. Cavanaugh, Kenion H. Blakeman, Tina E. Stacy, Stanley Pau, and J. Michael Ramsey
“A Field Emission Ion Source for High Pressure Mass Spectrometry” (poster)

27th ASMS Sanibel Conference on Mass Spectrometry: Security and Forensic Applications of Mass Spectrometry, Clearwater, FL (January 2015)

William M. Gilliland, Jr., Erin Redman, J. Scott Mellors and J. Michael Ramsey
“Coupling Microchip Capillary Electrophoresis and High Pressure Mass Spectrometry for Portable Applications" (Promoted poster talk)

The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences,
San Antonio, TX (October 2014)

Tom H. Linz, Wm Hampton Henley and J. Michael Ramsey
“Multiplexed Immunoassays Employing Microfluidic Digital Microwell Arrays” (poster)

Wm. Hampton Henley and J. Michael Ramsey
“Multi-Analyte Single Molecule Detection By Parallel Singleplex Reactions In A Compact Array” (poster)

Joshua P. Guerrette, Wm. Hampton Henley, and J. Michael Ramsey
Automatable on-chip Whole Blood Sample Preparation Including Microbead-based Protein and NA Target Extractions” (poster)

John M. Perry, Wm. Hampton Henley, and J. Michael Ramsey
“Development Of Plastic Microwell Arrays For Improved Replication Fidelity” (poster)

Erin A. Redman, Nicholas G. Batz, J. Scott Mellors, and J. Michael Ramsey
“Microchip CE-ESI-MS For The Separation Of Biological Samples” (poster)

Michael A. Tycon, Laurent D. Menard, and J. Michael Ramsey
“A Single-Molecule Nanofluidic Platform For The Precise Sizing Of DNA Fragments” (poster)

62nd American Society for Mass Spectrometry Conference, Baltimore, MD (June 2014)

Kevin Schultze, Kenion Blakeman, and J. Michael Ramsey
"Handheld Mass Spectrometry Enabled by Ultrahigh Pressure Operation using Air Buffer Gas" (oral)

William M. Gilliland, Jr., J. Scott Mellors, and J. Michael Ramsey
"Coupling Electrospray Ionization with High Pressure Mass Spectrometry" (poster)

Kenion H. Blakeman, Tina E. Stacy, Craig A. Cavanaugh, and J. Michael Ramsey, "Microfabricated Silicon Ion Traps for Portable, High Pressure Mass Spectrometry" (poster)

Andrew Hampton and J. Michael Ramsey
"Tandem Mass Spectrometry Using Miniature Cylindrical Ion Traps Operated at Ultra High Pressures" (poster)

Bruno Couper, Kevin Schultze, Dmitriy Chernookiy, Sorin Mitran and J. Michael Ramsey "Study of Impact of Gas Flow in a Microscale Ion Trap Operated at High Pressure" (poster)

Craig Cavanaugh, Kenion Blakeman, Tina Stacy, Stanley Pau, and J .Michael Ramsey "A Microfabricated Ionizer for High Pressure Mass Spectrometry" (poster)

Dmitriy Chernookiy, Bruno Couper, and J. Michael Ramsey
Optimizing of the Cylindrical Ion Trap Geometry Using Mesh Endcaps (poster)

41st International Symposium on High Performance Liquid Phase Separations and Related Techniques, New Orleans, LA (May 2014)

Erin A. Redman, Nicholas G. Batz, J. Scott Mellors and J. Michael Ramsey
"Intact Protein Separations via Microchip Capillary Electrophoresis Electrospray
Ionization Mass Spectrometry" (oral)

William M. Gilliland, Jr., Craig A. Cavanaugh, Kevin P. Schultze, J. Scott Mellors, and J. Michael Ramsey
"Development of a Miniaturized CE-ESI-MS System" (oral)

Nicholas G. Batz, J. Scott Mellors, Erin A. Redman and J. Michael Ramsey
"CE-ESI-MS Approaching the Diffusion-Limit: Theory and Practice" (oral)

J. Scott Mellors, William Black, Nicholas G. Batz, Erin A. Redman and J. Michael Ramsey
"Microfluidic Separation Devices with Integrated Electrospray Ionization" (oral)

William Black, J. Scott Mellors, and J. Michael Ramsey
"Integrating Solid Phase Extraction with Microchip Capillary Electrophoresis-Electrospray Ionization" (oral)

Pittcon 2014, Chicago, IL (March 2014)

Nicholas Batz, J. Scott Mellors and J. Michael Ramsey
"Surface Coating Method for Controlling Electroosmotic Flow for CE-ESI-MS" (oral)

William Black, J. Scott Mellors, and J. Michael Ramsey
"Development of a Multi-Dimensional Separations Platform" (oral)

Kevin Schultze, M. Bonner Denton, and J. Michael Ramsey
“Investigation of Pressure Tolerant Faraday Cup Detectors for High Pressure Mass Spectrometry" (oral)

Craig Cavanaugh, Kenion Blakeman, Tina Stacy, Stanley Pau, and J. Michael Ramsey
"A Microionizer for High Pressure Mass Spectrometry Using Air Buffer Gas” (oral)

Kenion Blakeman, Craig Cavanaugh, Kevin Schultze, and J. Michael Ramsey
“High Pressure Mass Spectrometry with Microscale Cylindrical Ion Trap Arrays” (oral)

Andrew Hampton, William M. Gilliland Jr., and J. Michael Ramsey
"Collision Induced Dissociation at 1 Torr in a Microscale Ion Trap Mass Spectrometer" (poster)

9th Harsh-Environment Mass Spectrometry Workshop, St. Pete Beach, FL (September 2013)

Kenion Blakeman, Craig Cavanaugh, and J. Michael Ramsey
“High Pressure Nitrogen and Air Mass Spectrometry with Microscale Ion Traps” (oral)

Craig Cavanaugh, Kenion Blakeman, Mac Gilliland, Bruno Coupier, and J. Michael Ramsey
“Trapping and Analysis of Externally Generated Ions in a Miniature Cylindrical Ion Trap” (oral)

Kevin P. Schultze, Kenion H. Blakeman, Craig A. Cavanaugh, Andrew S. Hampton, and J. Michael Ramsey. 
“Development of a Compact, Isobaric Chamber for High Pressure Mass Spectrometry of Ambient Organics” (poster)

61st American Society for Mass Spectrometry Conference, Minneapolis, MN (June 2013)

J. Scott Mellors, Nicholas G. Batz, Martin Green and J. Michael Ramsey
"Sub-second CE-ESI-MS using microfluidic devices and a novel method for acquiring high speed TOF-MS data" (oral)

Craig A. Cavanaugh, Kenion H. Blakeman, Tina E. Stacy, Derek W. Wolfe, Stanley Pau, J. Michael Ramsey
“Characterization of a low-power, pressure-tolerant microionizer” (poster)

Derek W. Wolfe, Travis M. Falconer, Roger P. Sperline, M. Bonner Denton, J. Michael Ramsey
"High-Pressure CIT Mass Spectrometry with a Solid-State CTIA Detector" (poster)

Kenion Blakeman and J. Michael Ramsey
"Increasing the Drive Frequency of a Microscale Cylindrical Ion Trap for Improved High Pressure Performance" (poster)

Kevin P. Schultze and J. Michael Ramsey
"Characterization of a Novel Ion Trap Geometry for Higher Capacity Trapping in Microscale Mass Spectrometry (poster)

Andrew Hampton, Kenion Blakeman, Bruno Coupier, Derek Wolfe, and J. Michael Ramsey
"Effects of Elevated Pressure on the Secular Frequencies of Ions in a Cylindrical Ion Trap" (poster)

Dmitriy Chernookiy, Bruno Coupier, and J. Michael Ramsey
"Miniature Cylindrical Ion Trap Geometry Optimization and Parameter Scaling" (poster)

Bruno Coupier, Sorin Mitran, Andrew Hampton, Kenion Blakeman and J. Michael Ramsey
"High pressure simulations investigations in miniature ion traps" (poster)

Sorin Mitran, Bruno Coupier, and J. Michael Ramsey,  “CITSIM: Collisional Ion Trap Simulator for trajectory computation under unsteady flow conditions ranging from near-vacuum to atmospheric pressure” (poster)

37th International Symposium on Capillary Chromatography, Palm Springs, CA (May 2013)

Will Black, J. Scott Mellors, and J. Michael Ramsey
"Development of a LC-CE-ESI Platform for Peptide Mapping Applications" (oral)

Pittcon 2013, Philadelphia, PA (March 2013)

Laurent D. Menard, Jinsheng Zhou, Chad E. Mair, Michael E. Woodson, Jean Pierre Alarie, and J. Michael Ramsey “Nanochannel Networks for Manipulating and Characterizing Single DNA Molecules” (oral)

Joseph C. Gaiteri, W. Hampton Henley, Jean Pierre Alarie, and J. Michael Ramsey
"A Microfluidic Assay for Determination of Kinase Phosphorylation" (oral)

29th International Symposium on MicroScale Bioseparations, Charlottesville, VA (March 2013)

Nicholas Batz, J. Scott Mellors, and J. Michael Ramsey
“Chemical Vapor Deposition of Aminopropyl Silanes for High Efficiency Microchip CE-ESI-MS” (oral)

Will Black, J. Scott Mellors and J. Michael Ramsey
"Integrating Solid Phase Extraction with Microchip CE-ESI" (oral)

Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC (November 2012)

Kenion Blakeman, Craig Cavanaugh, Derek Wolfe, and J. Michael Ramsey.  “Detecting Volatile Organic Compounds at High Pressure by Mass Spectrometry” (poster)

Craig A. Cavanaugh, Kenion H. Blakeman, Tina E. Stacy, Derek W. Wolfe, Stanley Pau, J. Michael Ramsey
“Towards a low-power, pressure-tolerant microionizer for handheld mass spectrometry” (poster)

Laurent D. Menard, Jinsheng Zhou, and J. Michael Ramsey
“Manipulation and Characterization of Single DNA Molecules in Nanofluidic Devices” (oral)

Microscopy and Microanalysis 2012, Phoenix, AZ (Jul. 29 – Aug. 2, 2012).

Laurent D. Menard, Jinsheng Zhou, Michael E. Woodson, Chad E. Mair, Jean Pierre Alarie, and J. Michael Ramsey “Focused Ion Beam Milled Nanochannels for Confinement Enabled DNA Single-Molecule Studies” (oral)

38th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Anaheim, CA (June 2012)

Nicholas Batz, J. Scott Mellors, and J. Michael Ramsey
“Development of Surface Coating Chemistry for Microchip CE-ESI” (poster)

Will Black, J. Scott Mellors, and J. Michael Ramsey
"Microchip CE-ESI-MS of Small Polar Molecules" (poster)

36th International Symposium on Capillary Chromatography, Riva del Garda, Italy (May 2012)

J. Scott Mellors, Nicholas G. Batz, and J. Michael Ramsey
“Microfluidic devices with integrated electrospray ionization for the analysis of biopharmaceuticals” (oral)

60th American Society for Mass Spectrometry Conference, Vancouver, BC (May 2012)

Derek W. Wolfe and J. Michael Ramsey
"High-Pressure Mass Spectrometry in Microscale Cylindrical Ion Traps" (poster)

Bruno Coupier, Derek W. Wolfe, Kenion Blakeman, Tina Stacy, Collin McKinney, Joseph C. Matteo, and J. Michael Ramsey "Development of a miniature ion trap mass spectrometer for applications requiring portability"(poster)

27th International Symposium on MicroScale Bioseparations and Analyses, Geneva, Switzerland (February 2012)

Jinsheng Zhou, Laurent D. Menard, Jean Pierre Alarie and J. Michael Ramsey
"Trapping single DNA molecules in three-dimensional nanofunnels"
(oral)

FEI FIB/DualBeam User Club Meeting, Hillsboro, OR (October, 2011)

Laurent D. Menard and J. Michael Ramsey,
"FIB Milled Nanochannels and Nanopores for DNA Single-Molecule Studies." (oral)

The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, WA (October 2011)

Shelly R. Beard, Wm. Hampton Henley, Jean Pierre Alarie, and J. Michael Ramsey
"Microwell Array PCR Chip for Study of Genetically Engineered Mouse Stem Cells"
(poster)

Menard, L. D.; Zhou, J. S.; Woodson, M. E.; Mair, C. E.; Alarie, J. P.; Ramsey, J. M.
"Single Molecule Dynamics of DNA during Electrokinetic Transport through Nanofluidic Channels."
(poster)

Woodson, M. E.; Menard, L. D.; Mair, C. E.; Alarie, J. P.; Ramsey, J. M.
"Transverse Conductance Measurements of Single DNA Molecules."
(poster)

Emily Oblath, Wm. Hampton Henley, Jean Pierre Alarie, and J. Michael Ramsey
"A Microfluidic Chip Combining DNA Extraction and Real-time PCR For Identifying Bacteria in Saliva"
(poster)

59th American Society for Mass Spectrometry Conference, Denver, CO (June 2011)

Derek W. Wolfe, Dmitriy Chernookiy, Tina Stacy, Matthew Verber, Collin McKinney and J. Michael Ramsey
"RF Amplifier Optimization for Improved Resolution in Microscale Cylindrical Ion Traps"
(poster)

26th International Symposium on MicroScale Bioseparations, San DIego, CA (May 2011)

Emily Oblath, Wm. Hampton Henley, Jean Pierre Alarie, and J. Michael Ramsey
"Microfluidic Chip-based Genomic DNA Extraction and Real-time PCR for the identification of Bacteria in Saliva"
(oral)

34th International Symposium on Capillary Chromatography, Riva del Garda, Italy (May 2010)

Laurent Menard and J. Michael Ramsey
“DNA Transport In Nanochannels: The Role Of Entropy And Single-Molecule Dynamics”
(poster)

J. Scott Mellors, Andrew G. Chambers, and J. Michael Ramsey
"Microchip Separations with Integrated Electrospray Ionization MS"
(poster)

Joshua Herr, Soren Johnson, Jean Pierre Alarie, Norman Sharpless, and J. Michael Ramsey
"Microfluidic Flow Cytometry for Blood Cell Enumeration"
(oral)

58th American Society for Mass Spectrometry Conference, Salt Lake City, UT (May 2010)

Derek W. Wolfe, Travis M. Falconer, Joseph C. Matteo, and J. Michael Ramsey
"In situ Optimization of Microscale Cylindrical Ion Trap Geometry"
(poster)

Travis M. Falconer, Derek W. Wolfe, Collin J. McKinney, Wit Wisniewski,
M. Bonner Denton, J. Michael Ramsey
"High Pressure Ion Detection for Miniaturized Mass Spectrometers"
(poster)

27th Triangle Chromatography Discussion Group Conference, Raleigh, NC (May 2010)

Andrew G. Chambers, J. Scott Mellors, and J. Michael Ramsey
"Analysis of Monoclonal Antibodies by LC/CE-MS"
(poster)

Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Orlando, FL (February 2010)

Joshua Herr, Soren Johnson, Jean Pierre Alarie, Norman Sharpless, and J. Michael Ramsey
"Applications of Microfluidic Flow Cytometry"
(oral)

April L. R. Holland, Laurent D. Menard, and J. Michael Ramsey
"Layered Modification of Solid-State Nanopores for Detecting Protein-Antibody Complexes"
(oral)